Endocrine Abstracts

Introduction: Diagnosis of Cushing Syndrome (CS) is challenging due to its various non-specific symptoms, and multiple endogenous and exogenous causes. The incidence of endogenous CS is rare and estimated at 2 to 3 cases per million inhabitants per year in Europe (1). Primary bilateral macronodular adrenal hyperplasia (PBMAH) is an uncommon cause of endogenous ACTH-independent CS. It is a benign condition, characterized by the presence of bilateral macronodules (>1 cm), an...

Background: Adrenal insufficiency is a rare but potentially life threatening complication of the antiphospholipid antibody syndrome (APS). The adrenal gland is the most commonly involved endocrine organ with adrenal insufficiency reported in 0.4% of APS cases. Adrenal failure more often follows other thromboembolic manifestations of APS.Case report: We report a 25-year-old male with systemic lupus erythematosus (SLE) with antiphospholipid syndrome (tripl...

Pheochromocytoma is a rare catecholamine-secreting tumor with variable clinical manifestations. A possible cardiac presentation is acute left ventricular wall motion abnormality in the heart also known as the Takotsubo syndrome. Takotsubo stress cardiomyopathy was first described in 1990 in Japan and current knowledge remains limited. We report a case of pheochromocytoma-induced Takotsubo syndrome. A 43-year-old woman acutely developed nausea, severe chest pain, and dyspnoea d...

Background : The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is of an unprecedented scale, with an ever-growing impact on healthcare systems. The clinical presentation of coronavirus disease 2019 (COVID-19) is diverse, ranging from asymptomatic illness to respiratory failure requiring admission to the intensive care unit (ICU). Risk factors for severe presentation include old age, male gender, underlying comorbidities such as metabolic syndr...